Brgy. Lusod is an interior barangay of Salcedo. It is located 9.5 kilometers at the northern part of the town proper of Salcedo, 29.5 kilometers from the town proper of Guiuan, and 96.5 kilometres south east of Borongan City (the capital City of E. Samar).
Brgy. Lusod is almost 5 kilometers away from the national highway (where all kinds of public utility vehicles are available during night and day times). Brgy. Lusod is accessible by any land transportation vehicles such as jeepneys, single motorcycle, trucks, and tricycle.
The Barangay has a total land area of 291.8 hectares (source: MENRO Salcedo-2009). The land use distribution is not yet planned, hence, there is no specific measure of areas for residential, agricultural, institutional and forest land.