Seguinon is an interior barangay of Salcedo. It is located 7.5 kilometers northwest of the town proper of Salcedo, 25.5 kilometers from the town proper of Guiuan, and 87.5 kilometers south east of Borongan City (the capital City of E. Samar). From the east you can found Barangay Iberan, on West is Barangay Caridad, in North is Barangay Abejao,
Matarinao Bay and on the South is Barangay Talangdawan/ Barangay Naparaan.
Barangay Seguinon is accessible by trucks, mini bus, jeep and single motorcycle. Public utility vehicles are only available during daytime. People in the community prefer to walk in going out to the national highway because of limited vehicles.
The Barangay has a total land area of 462.93 hectares (source: MENRO Salcedo-2009). The land use distribution is not yet planned. Hence, there is no specific measure of areas for residential, institutional, agricultural, etc.