Barangay Sta. Cruz is located at the hill part of the Municipality of Salcedo, Eastern Samar. It is bounded on the North of Barangay Taclaon; on the South Barangay Cagaut; on the west part Leyte Gulf and on the East part is Barangay Cantomoja. It is Fourteen and a half kilometers (14kms) from Salcedo proper.
The Barangay can be reached through paved and rugged roads from Salcedo. Means of transportation for this area could be “habal-habal”, tricycle or by foot.
The Barangay has a total land area of 268.54 hectares (source: MENRO Salcedo-2009). The land use distribution is not yet planned; hence, there is no specific measure of areas for residential, institutional, agricultural, etc.
The area is characterized as hilly and mountainous. The slope range from 18 to 50 degrees. The soil type is clay loam. The water bodies fresh (boreholes water), to high salinity (sea water).